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Accupril Hypertension
on Sale at Alfaus Prescription Drugs Pharmacy
ACCUPRIL is indicated for the treatment of mild to
moderate hypertension. ACCUPRIL is effective as monotherapy or
concomitantly with diuretics in patients with hypertension. |
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Accupril |
30 - 5 mg Tablets |
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Male
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Accupril |
60 - 5 mg Tablets |
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Accupril |
90 - 5 mg Tablets |
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Accupril |
30 - 10 mg Tablets |
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Accupril |
60 - 10 mg Tablets |
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Accupril |
90 - 10 mg Tablets |
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Accupril |
30 - 20 mg Tablets |
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Female
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Accupril |
60 - 20 mg Tablets |
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Accupril |
90 - 20 mg Tablets |
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Accupril |
30 - 40 mg Tablets |
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Accupril |
60 - 40 mg Tablets |
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Accupril |
90 - 40 mg Tablets |
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The following
information is intended to supplement, not substitute for, the expertise and
judgment of your physician, pharmacist or other healthcare professional. It
should not be construed to indicate that use of the drug is safe,
appropriate, or effective for you. Consult your healthcare professional
before using this drug.
Online Prescription Accupril Use
Indication:
ACCUPRIL is indicated for the treatment of unresponsive systolic left
ventricular failure of various aetiologies in which afterload reduction is
advocated.
Hypertension:
Monotherapy: The recommended initial dosage of ACCUPRIL in patients not on
diuretics is 10 mg once daily. Depending upon clinical response, patient's
dosage may be titrated (by doubling the dose) to a maintenance dosage of 20
to 40 mg/day given as a single dose or divided into two doses. Generally,
dosage adjustments should be made at intervals of four weeks or according to
patient's response. Long-term control is maintained in most patients with a
single daily dosage regimen.
Antihypertensive activity commences within one hour with peak effects usually
achieved by two to four hours after dosing. Achievement of maximum blood
pressure lowering effects may require two weeks of therapy in some patients.
Concomitant Diuretics: In patients who are also being treated with a
diuretic, the initial dosage of ACCUPRIL is 5 mg in order to determine if
excess hypotension will occur. The dosage should subsequently be titrated (as
described above) to the optimal response (see SIDE EFFECTS AND SPECIAL
PRECAUTIONS).
Congestive Heart Failure:
The recommended initial dosage in patients with congestive heart failure due
to unresponsive systolic left ventricular failure of various aetiologies in
which afterload reduction is advocated, is a single 5 mg dose, following
which the patient should be monitored closely for symptomatic hypotension.
Patients may be titrated up to 40 mg per day given in two doses with
concomitant diuretic and/or cardiac glycoside therapy. Patients can, however,
normally be maintained effectively on doses of 10 to 20 mg per day given in
one or two doses with concomitant therapy.
Hypertension Medication
Accupril Side Effects:
The most frequent
clinical adverse reactions in controlled trials with accupril were (in
descending order of frequency) headache, dizziness, rhinitis, coughing, upper
respiratory tract infection, fatigue, dyspepsia, nausea and vomiting, myalgia,
abdominal pain, diarrhoea, insomnia, paresthesia, nervousness, asthenia,
hypotension and leucopenia.
Less frequent adverse events that have been reported include: palpitations,
vasodilatation, dry mouth or throat, pancreatitis, vertigo, nervousness,
depression, somnolence, pruritus, rash, exfoliative dermatitis, pemphigus,
increased perspiration, alopecia, urinary tract infection, impotence, edema,
arthralgia, hemolytic anaemia, and angioedema.
Creatinine and Blood Urea Nitrogen: Increases (>1,25 times the upper limit of
normal) in serum creatinine and blood urea nitrogen may occur especially with
concomitant diuretic therapy.
Precautions on using
Accupril Hypertension Medication
Angioedema: Angioedema,
including laryngeal edema, may occur, especially following the first dose of
ACCUPRIL. Patients should be so advised and told to report immediately any
signs or symptoms suggesting angioedema (swelling of face, eyes, lips,
tongue, difficulty in breathing) and to discontinue medication until they
have consulted with their physician.
If laryngeal stridor or angioedema of the face, tongue, or glottis occur,
treatment with ACCUPRIL should be discontinued immediately, the patient
treated appropriately in accordance with accepted medical care, and carefully
observed until the swelling disappears. Angioedema associated with laryngeal
involvement may be fatal. Where there is involvement of the tongue, glottis,
or larynx likely to cause airway obstruction, appropriate therapy e.g.,
subcutaneous adrenalin solution 1:1000 (0,3 to 0,5 mL) should be promptly
administered.
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